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The Abbott Cell Dyn 3500 automated hematology analyzer employs dual technologies to provide the basis for a five-part WBC differential. Multi-Angle Polarized Scatter Separation (M.A.P.S.S.) provides the primary white blood cell count, all differential information, and reticulocyte analysis, while impedence provides additional information in the presence of fragile lymphocytes and hypotonically resistant red blood cells.